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Proteinase-activated receptor 2 and disease biomarkers in cerebrospinal fluid in cases with autopsy-confirmed prion diseases and other neurodegenerative diseases

BACKGROUND: Proteinase-activated receptor 2 (PAR-2) has been shown to promote both neurotoxic and neuroprotective effects. Similarly, other routinely used nonspecific markers of neuronal damage can be found in cerebrospinal fluid (CSF) and can be used as biomarkers for different neurodegenerative di...

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Detalles Bibliográficos
Autores principales: Rohan, Zdenek, Smetakova, Magdalena, Kukal, Jaromir, Rusina, Robert, Matej, Radoslav
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392746/
https://www.ncbi.nlm.nih.gov/pubmed/25886404
http://dx.doi.org/10.1186/s12883-015-0300-x