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Megakaryoblastic leukemia-1 is required for the development of bleomycin-induced pulmonary fibrosis
BACKGROUND: Fibrosing disorders of the lung, such as idiopathic pulmonary fibrosis, are characterized by progressive extracellular matrix accumulation that is driven by myofibroblasts. The transcription factor megakaryoblastic leukemia-1 (MKL1) mediates myofibroblast differentiation in response to s...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392778/ https://www.ncbi.nlm.nih.gov/pubmed/25885656 http://dx.doi.org/10.1186/s12931-015-0206-6 |