Pharmacokinetics of nalbuphine hydrochloride extended release tablets in hemodialysis patients with exploratory effect on pruritus

BACKGROUND: Uremic pruritus is a common and deleterious condition among hemodialysis (HD) patients. Central gating of μ/κ opiate circuitry plays an important role in mediating and countering pruritogenic sensation. The objective of this study was to assess the safety and pharmacokinetics (PK) of the...

Descripción completa

Detalles Bibliográficos
Autores principales: Hawi, Amale, Alcorn, Harry, Berg, Jolene, Hines, Carey, Hait, Howard, Sciascia, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392787/
https://www.ncbi.nlm.nih.gov/pubmed/25885112
http://dx.doi.org/10.1186/s12882-015-0043-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392787/
https://www.ncbi.nlm.nih.gov/pubmed/25885112
http://dx.doi.org/10.1186/s12882-015-0043-3

Ejemplares similares