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Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer

BACKGROUND: The VEGF pathway has become an important therapeutic target in lung cancer, where VEGF has long been established as a potent pro-angiogenic growth factor expressed by many types of tumors. While Bevacizumab (Avastin) has proven successful in increasing the objective tumor response rate a...

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Detalles Bibliográficos
Autores principales: Barr, Martin P, Gray, Steven G, Gately, Kathy, Hams, Emily, Fallon, Padraic G, Davies, Anthony Mitchell, Richard, Derek J, Pidgeon, Graham P, O’Byrne, Kenneth J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392793/
https://www.ncbi.nlm.nih.gov/pubmed/25889301
http://dx.doi.org/10.1186/s12943-015-0310-8