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Vascular endothelial growth factor is an autocrine growth factor, signaling through neuropilin-1 in non-small cell lung cancer
BACKGROUND: The VEGF pathway has become an important therapeutic target in lung cancer, where VEGF has long been established as a potent pro-angiogenic growth factor expressed by many types of tumors. While Bevacizumab (Avastin) has proven successful in increasing the objective tumor response rate a...
Autores principales: | Barr, Martin P, Gray, Steven G, Gately, Kathy, Hams, Emily, Fallon, Padraic G, Davies, Anthony Mitchell, Richard, Derek J, Pidgeon, Graham P, O’Byrne, Kenneth J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392793/ https://www.ncbi.nlm.nih.gov/pubmed/25889301 http://dx.doi.org/10.1186/s12943-015-0310-8 |
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