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Simultaneous application of bevacizumab and anti-CTGF antibody effectively suppresses proangiogenic and profibrotic factors in human RPE cells

PURPOSE: Retinal pigment epithelial (RPE) cells play key roles in the development of choroidal neovascularization and subsequent fibrosis. We investigated the impact of bevacizumab, antihuman vascular endothelial growth factor (VEGF) antibody, and anticonnective tissue growth factor (anti-CTGF) neut...

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Detalles Bibliográficos
Autores principales: Bagheri, Abouzar, Soheili, Zahra-Soheila, Ahmadieh, Hamid, Samiei, Shahram, Sheibani, Nader, Astaneh, Shamila Darvishalipour, Kanavi, Mozhgan Rezaei, Mohammadian, Azam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Vision 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392827/
https://www.ncbi.nlm.nih.gov/pubmed/25883524