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The endothelial deprotection hypothesis for lupus pathogenesis: the dual role of C1q as a mediator of clearance and regulator of endothelial permeability
Systemic lupus erythematosus (SLE) is a heterogeneous multifactorial systemic autoimmune disease affecting several organs. SLE can start relatively early in life and results in impaired quality of life and shortened life expectancy because of a gradual disease progression leading to cardiovascular,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2015
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392829/ https://www.ncbi.nlm.nih.gov/pubmed/25901277 http://dx.doi.org/10.12688/f1000research.6075.2 |