Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective

BACKGROUND: The impact of cell-composition effects in analysis of DNA methylation data is now widely appreciated. With the availability of a reference data set consisting of DNA methylation measurements on isolated cell types, it is possible to impute cell proportions and adjust for them, but there...

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Detalles Bibliográficos
Autores principales: Houseman, E Andres, Kelsey, Karl T, Wiencke, John K, Marsit, Carmen J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Methodology Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392865/
https://www.ncbi.nlm.nih.gov/pubmed/25887114
http://dx.doi.org/10.1186/s12859-015-0527-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392865/
https://www.ncbi.nlm.nih.gov/pubmed/25887114
http://dx.doi.org/10.1186/s12859-015-0527-y

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