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Cell-composition effects in the analysis of DNA methylation array data: a mathematical perspective
BACKGROUND: The impact of cell-composition effects in analysis of DNA methylation data is now widely appreciated. With the availability of a reference data set consisting of DNA methylation measurements on isolated cell types, it is possible to impute cell proportions and adjust for them, but there...
Autores principales: | Houseman, E Andres, Kelsey, Karl T, Wiencke, John K, Marsit, Carmen J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392865/ https://www.ncbi.nlm.nih.gov/pubmed/25887114 http://dx.doi.org/10.1186/s12859-015-0527-y |
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