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Gene Expression and Cytokine Profile Correlate With Mycobacterial Growth in a Human BCG Challenge Model

Background. Bacillus Calmette-Guerin (BCG) vaccine is the most widely administered vaccine in the world, yet its mechanism of action remains unclear. We hypothesize that certain immune pathways are associated with reduced mycobacterial growth following BCG challenge in human volunteers. Methods. We...

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Detalles Bibliográficos
Autores principales: Matsumiya, Magali, Satti, Iman, Chomka, Agnieszka, Harris, Stephanie A., Stockdale, Lisa, Meyer, Joel, Fletcher, Helen A., McShane, Helen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392868/
https://www.ncbi.nlm.nih.gov/pubmed/25381367
http://dx.doi.org/10.1093/infdis/jiu615