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Gene Expression and Cytokine Profile Correlate With Mycobacterial Growth in a Human BCG Challenge Model
Background. Bacillus Calmette-Guerin (BCG) vaccine is the most widely administered vaccine in the world, yet its mechanism of action remains unclear. We hypothesize that certain immune pathways are associated with reduced mycobacterial growth following BCG challenge in human volunteers. Methods. We...
Autores principales: | Matsumiya, Magali, Satti, Iman, Chomka, Agnieszka, Harris, Stephanie A., Stockdale, Lisa, Meyer, Joel, Fletcher, Helen A., McShane, Helen |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392868/ https://www.ncbi.nlm.nih.gov/pubmed/25381367 http://dx.doi.org/10.1093/infdis/jiu615 |
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