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Cyclin D1 Represses Gluconeogenesis via Inhibition of the Transcriptional Coactivator PGC1α

Hepatic gluconeogenesis is crucial to maintain normal blood glucose during periods of nutrient deprivation. Gluconeogenesis is controlled at multiple levels by a variety of signal transduction and transcriptional pathways. However, dysregulation of these pathways leads to hyperglycemia and type 2 di...

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Detalles Bibliográficos
Autores principales: Bhalla, Kavita, Liu, Wan-Ju, Thompson, Keyata, Anders, Lars, Devarakonda, Srikripa, Dewi, Ruby, Buckley, Stephanie, Hwang, Bor-Jang, Polster, Brian, Dorsey, Susan G., Sun, Yezhou, Sicinski, Piotr, Girnun, Geoffrey D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392904/
https://www.ncbi.nlm.nih.gov/pubmed/24947365
http://dx.doi.org/10.2337/db13-1283