Withaferin A Induces Proteasome-Dependent Degradation of Breast Cancer Susceptibility Gene 1 and Heat Shock Factor 1 Proteins in Breast Cancer Cells

The purpose of this study was to examine the regulation of prosurvival factors heat shock factor 1 (HSF1) and breast cancer susceptibility gene 1 (BRCA1) by a natural withanolide withaferin A (WA) in triple negative breast cancer cell lines MDA-MB-231 and BT20. Western analysis was used to examine a...

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Detalles Bibliográficos
Autores principales: Zhang, Xuan, Timmermann, Barbara, Samadi, Abbas K., Cohen, Mark S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scholarly Research Network 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392979/
https://www.ncbi.nlm.nih.gov/pubmed/25969759
http://dx.doi.org/10.5402/2012/707586

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392979/
https://www.ncbi.nlm.nih.gov/pubmed/25969759
http://dx.doi.org/10.5402/2012/707586

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