Biochemical Studies on Methylglyoxal-Mediated Glycated Histones: Implications for Presence of Serum Antibodies against the Glycated Histones in Patients with Type 1 Diabetes Mellitus

Reactive carbonyl species (RCS) mainly reacts with lysine and arginine residues of proteins to form advanced glycation end products (AGEs). Histone was glycoxidated with glyoxal and methylglyoxal. It was characterized by polyacrylamide gel electrophoresis and quenching studies involving penicillamin...

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Detalles Bibliográficos
Autores principales: Ansari, Nadeem A., Dash, Debabrata
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392999/
https://www.ncbi.nlm.nih.gov/pubmed/25937957
http://dx.doi.org/10.1155/2013/198065

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392999/
https://www.ncbi.nlm.nih.gov/pubmed/25937957
http://dx.doi.org/10.1155/2013/198065

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