The Growth and Aggressive Behavior of Human Osteosarcoma Is Regulated by a CaMKII-Controlled Autocrine VEGF Signaling Mechanism

Osteosarcoma (OS) is a hyperproliferative malignant tumor that requires a high vascular density to maintain its large volume. Vascular Endothelial Growth Factor (VEGF) plays a crucial role in angiogenesis and acts as a paracrine and autocrine agent affecting both endothelial and tumor cells. The alp...

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Detalles Bibliográficos
Autores principales: Daft, Paul G., Yang, Yang, Napierala, Dobrawa, Zayzafoon, Majd
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393114/
https://www.ncbi.nlm.nih.gov/pubmed/25860662
http://dx.doi.org/10.1371/journal.pone.0121568

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393114/
https://www.ncbi.nlm.nih.gov/pubmed/25860662
http://dx.doi.org/10.1371/journal.pone.0121568

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