Filamin-A Increases the Stability and Plasma Membrane Expression of Polycystin-2

Polycystin-2 (PC2), encoded by the PKD2 gene, is mutated in ~15% of autosomal dominant polycystic kidney disease. Filamins are actin-binding proteins implicated in scaffolding and membrane stabilization. Here we studied the effects of filamin on PC2 stability using filamin-deficient human melanoma M...

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Detalles Bibliográficos
Autores principales: Wang, Qian, Zheng, Wang, Wang, Zuocheng, Yang, JungWoo, Hussein, Shaimaa, Tang, Jingfeng, Chen, Xing-Zhen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393133/
https://www.ncbi.nlm.nih.gov/pubmed/25861040
http://dx.doi.org/10.1371/journal.pone.0123018

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393133/
https://www.ncbi.nlm.nih.gov/pubmed/25861040
http://dx.doi.org/10.1371/journal.pone.0123018

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