Carbidopa-Based Modulation of the Functional Effect of the AAV2-hAADC Gene Therapy in 6-OHDA Lesioned Rats

Progressively blunted response to L-DOPA in Parkinson’s disease (PD) is a critical factor that complicates long-term pharmacotherapy in view of the central importance of this drug in management of the PD-related motor disturbance. This phenomenon is likely due to progressive loss of one of the key e...

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Detalles Bibliográficos
Autores principales: Ciesielska, Agnieszka, Sharma, Nitasha, Beyer, Janine, Forsayeth, John, Bankiewicz, Krystof
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393141/
https://www.ncbi.nlm.nih.gov/pubmed/25860990
http://dx.doi.org/10.1371/journal.pone.0122708

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393141/
https://www.ncbi.nlm.nih.gov/pubmed/25860990
http://dx.doi.org/10.1371/journal.pone.0122708

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