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Contrasting effects of hyperoxia on GM-CSF gene transcription in alveolar epithelial cells and T cells

Granulocyte/macrophage colony-stimulating factor (GM-CSF) is critically important for normal pulmonary innate immunity and for functional maturation of alveolar macrophages. Alveolar epithelial cells (AEC) are a major source of GM-CSF in the lung and express this growth factor constitutively, wherea...

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Detalles Bibliográficos
Autores principales: Sturrock, Anne, Baker, Jessica A, Mir-Kasimov, Mustafa, Paine, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393158/
https://www.ncbi.nlm.nih.gov/pubmed/25747588
http://dx.doi.org/10.14814/phy2.12324