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The caspase inhibitor zVAD increases lung inflammation in pneumovirus infection in mice

Severe respiratory syncytial virus (RSV) disease is a frequent cause of acute respiratory distress syndrome (ARDS) in young children, and is associated with marked lung epithelial injury and neutrophilic inflammation. Experimental studies on ARDS have shown that inhibition of apoptosis in the lungs...

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Detalles Bibliográficos
Autores principales: van den Berg, Elske, Bal, Suzanne M, Kuipers, Maria T, Matute-Bello, Gustavo, Lutter, René, Bos, Albert P, van Woensel, Job B M, Bem, Reinout A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393166/
https://www.ncbi.nlm.nih.gov/pubmed/25780096
http://dx.doi.org/10.14814/phy2.12332