Iron depletion results in Src kinase inhibition with associated cell cycle arrest in neuroblastoma cells

Iron is required for cellular proliferation. Recently, using systematic time studies of neuroblastoma cell growth, we better defined the G1 arrest caused by iron chelation to a point in mid-G1, where cyclin E protein is present, but the cyclin E/CDK2 complex kinase activity is inhibited. In this stu...

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Detalles Bibliográficos
Autores principales: Siriwardana, Gamini, Seligman, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393172/
https://www.ncbi.nlm.nih.gov/pubmed/25825542
http://dx.doi.org/10.14814/phy2.12341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393172/
https://www.ncbi.nlm.nih.gov/pubmed/25825542
http://dx.doi.org/10.14814/phy2.12341

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