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Iron depletion results in Src kinase inhibition with associated cell cycle arrest in neuroblastoma cells
Iron is required for cellular proliferation. Recently, using systematic time studies of neuroblastoma cell growth, we better defined the G1 arrest caused by iron chelation to a point in mid-G1, where cyclin E protein is present, but the cyclin E/CDK2 complex kinase activity is inhibited. In this stu...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BlackWell Publishing Ltd
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393172/ https://www.ncbi.nlm.nih.gov/pubmed/25825542 http://dx.doi.org/10.14814/phy2.12341 |