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Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts

Previous studies have shown that protease-activated receptors (PARs) play an important role in various physiological processes. In the present investigation, we determined the expression of PARs on human lung fibroblasts (HLF-1) and whether they were involved in cellular differentiation and pro-infl...

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Detalles Bibliográficos
Autores principales: Asokananthan, Nithiananthan, Lan, Rommel S, Graham, Peter T, Bakker, Anthony J, Tokanović, Ana, Stewart, Geoffrey A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393203/
https://www.ncbi.nlm.nih.gov/pubmed/25663523
http://dx.doi.org/10.14814/phy2.12295