Cargando…

Activation of protease-activated receptors (PARs)-1 and -2 promotes alpha-smooth muscle actin expression and release of cytokines from human lung fibroblasts

Previous studies have shown that protease-activated receptors (PARs) play an important role in various physiological processes. In the present investigation, we determined the expression of PARs on human lung fibroblasts (HLF-1) and whether they were involved in cellular differentiation and pro-infl...

Descripción completa

Detalles Bibliográficos
Autores principales:	Asokananthan, Nithiananthan, Lan, Rommel S, Graham, Peter T, Bakker, Anthony J, Tokanović, Ana, Stewart, Geoffrey A
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BlackWell Publishing Ltd 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393203/ https://www.ncbi.nlm.nih.gov/pubmed/25663523 http://dx.doi.org/10.14814/phy2.12295

Ejemplares similares

Serological Assessment of Activated Fibroblasts by alpha-Smooth Muscle Actin (α-SMA): A Noninvasive Biomarker of Activated Fibroblasts in Lung Disorders()()
por: Holm Nielsen, Signe, et al.
Publicado: (2018)

A function for filamentous alpha-smooth muscle actin: retardation of motility in fibroblasts
Publicado: (1996)

Expression of alpha-smooth muscle actin in liver diseases.
por: Yu, E., et al.
Publicado: (1993)

Smooth Muscle-Alpha Actin Inhibits Vascular Smooth Muscle Cell Proliferation and Migration by Inhibiting Rac1 Activity
por: Chen, Lihua, et al.
Publicado: (2016)

Sequential activation of alpha-actin genes during avian cardiogenesis: vascular smooth muscle alpha-actin gene transcripts mark the onset of cardiomyocyte differentiation
Publicado: (1988)

Heterogeneity of microvascular pericytes for smooth muscle type alpha- actin
Publicado: (1991)

Alpha-smooth muscle actin-positive cancer-associated fibroblasts secreting osteopontin promote growth of luminal breast cancer
por: Muchlińska, Anna, et al.
Publicado: (2022)

Chemical Tools to Image the Activity of PAR-Cleaving Proteases
por: Lee, Irene Y., et al.
Publicado: (2023)

Immunohistochemical study of alpha-smooth muscle actin in odontogenic cysts and tumors
por: Annegowda, Vidya Mallipattana, et al.
Publicado: (2018)

Protease-activated receptor (PAR)-2 is required for PAR-1 signalling in pulmonary fibrosis
por: Lin, Cong, et al.
Publicado: (2015)

The interstitial expression of alpha-smooth muscle actin in glomerulonephritis is associated with renal function
por: Novakovic, Zana Saratlija, et al.
Publicado: (2012)

Alpha-Smooth Muscle Actin-Positive Perivascular Cells in Diabetic Retina and Choroid
por: Kim, Soo Jin, et al.
Publicado: (2020)

A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation
Publicado: (1986)

A protease activated receptor-2 (PAR-2) activating peptide, tc-LIGRLO-NH(2), induces protease release from mast cells: role in TNF degradation
por: Alshurafa, Hashem N, et al.
Publicado: (2004)

Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
Publicado: (1993)

A subtype of cancer-associated fibroblasts with lower expression of alpha-smooth muscle actin suppresses stemness through BMP4 in oral carcinoma
por: Patel, Ankit Kumar, et al.
Publicado: (2018)

Histone 2B Facilitates Plasminogen-Enhanced Endothelial Migration through Protease-Activated Receptor 1 (PAR1) and Protease-Activated Receptor 2 (PAR2)
por: Das, Mitali, et al.
Publicado: (2022)

Protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

α-smooth muscle actin-positive fibroblasts correlate with poor survival in hepatocellular carcinoma
por: PARIKH, JIGNESH G., et al.
Publicado: (2014)

Protease-activated receptors (PARs)—biology and role in cancer invasion and metastasis
por: Wojtukiewicz, Marek Z., et al.
Publicado: (2015)

Correction to: protease-activated receptors (PARs): mechanisms of action and potential therapeutic modulators in PAR-driven inflammatory diseases
por: Heuberger, Dorothea M., et al.
Publicado: (2019)

Complement factor C4a does not activate protease‐activated receptor 1 (PAR1) or PAR4 on human platelets
por: Han, Xu, et al.
Publicado: (2020)

Interferon gamma inhibits both proliferation and expression of differentiation-specific alpha-smooth muscle actin in arterial smooth muscle cells
Publicado: (1989)

Cell cycle versus density dependence of smooth muscle alpha actin expression in cultured rat aortic smooth muscle cells
Publicado: (1988)

Immunohistochemical study of the expression of alpha-smooth muscle actin and the proliferation marker Ki-67 of glomerulonephritis.
por: Kim, O.
Publicado: (2001)

Alpha Smooth Muscle Actin Expression in a Case of Ameloblastic Carcinoma: a Case Report
por: Roy, Swati, et al.
Publicado: (2013)

Protocol to detect smooth muscle actin-alpha and measure oxidative damage in neonatal mouse intestine
por: Hu, Shing, et al.
Publicado: (2022)

Emerging Roles of Protease-Activated Receptors (PARs) in the Modulation of Synaptic Transmission and Plasticity
por: Price, Rachel, et al.
Publicado: (2021)

Transient early neurotrophin release and delayed inflammatory cytokine release by microglia in response to PAR-2 stimulation
por: Chen, Chen-wen, et al.
Publicado: (2012)

Humanizing the Protease-Activated Receptor (PAR) Expression Profile in Mouse Platelets by Knocking PAR1 into the Par3 Locus Reveals PAR1 Expression Is Not Tolerated in Mouse Platelets
por: French, Shauna L., et al.
Publicado: (2016)

Distinctive G Protein-Dependent Signaling by Protease-Activated Receptor 2 (PAR2) in Smooth Muscle: Feedback Inhibition of RhoA by cAMP-Independent PKA
por: Sriwai, Wimolpak, et al.
Publicado: (2013)

p21/waf1 and Smooth-Muscle Actin α Expression in Stromal Fibroblasts of Oral Cancers
por: Chatzistamou, Ioulia, et al.
Publicado: (2010)

Calcium Mobilization And Protein Kinase C Activation Downstream Of Protease Activated Receptor 4 (PAR4) Is Negatively Regulated By PAR3 In Mouse Platelets
por: Arachiche, Amal, et al.
Publicado: (2013)

Tenascin-C and alpha-smooth muscle actin positive cells are increased in the large airways in patients with COPD
por: Löfdahl, Magnus, et al.
Publicado: (2011)

Significance of alpha smooth muscle actin expression in traumatic painful neuromas: a pilot study in rats
por: Weng, Weidong, et al.
Publicado: (2016)

Alpha-Smooth Muscle Actin Expression and Parafoveal Blood Flow Pathways Are Altered in Preclinical Diabetic Retinopathy
por: An, Dong, et al.
Publicado: (2022)

Protease-activated receptor-1 (PAR-1): a promising molecular target for cancer
por: Liu, Xuan, et al.
Publicado: (2017)

Protease-Activated Receptor 4 (PAR4): A Promising Target for Antiplatelet Therapy
por: Rwibasira Rudinga, Gamariel, et al.
Publicado: (2018)

Predictive value of protease‐activated receptor‐2 (PAR(2)) in cervical cancer metastasis
por: He, Shengnan, et al.
Publicado: (2020)

Role of protease‐activated receptor‐1 (PAR‐1) in the glomerular filtration barrier integrity
por: Medipally, Ajay, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_8j5q5isj4soshtqnu1m3cvcmor