Synergistic induction of CCL2/MCP-1 expression driven by oncostatin M and IL-1β in human proximal tubular cells depends on STAT3 and p65 NFκB/RelA

In response to tubular injury, production, and secretion of cytokines, chemokines or extracellular matrix components by human proximal tubular epithelial cells (PTC) directly contribute to the development of tubulointerstitial inflammation and fibrosis. Here, we report a novel stimulatory and synerg...

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Detalles Bibliográficos
Autores principales: Sarközi, Rita, Corazza, Ulrike, Osterkamp, Jan-Philipp, Pirklbauer, Markus, Mayer, Gert, Schramek, Herbert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2015
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393206/
https://www.ncbi.nlm.nih.gov/pubmed/25713326
http://dx.doi.org/10.14814/phy2.12298

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393206/
https://www.ncbi.nlm.nih.gov/pubmed/25713326
http://dx.doi.org/10.14814/phy2.12298

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