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Requirement of DLG1 for Cardiovascular Development and Tissue Elongation during Cochlear, Enteric, and Skeletal Development: Possible Role in Convergent Extension
The Dlg1 gene encodes a member of the MAGUK protein family involved in the polarization of epithelial cells. Null mutant mice for the Dlg1 gene (Dlg1(-/-) mice) exhibit respiratory failure and cyanosis, and die soon after birth. However, the cause of this neonatal lethality has not been determined....
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393223/ https://www.ncbi.nlm.nih.gov/pubmed/25860837 http://dx.doi.org/10.1371/journal.pone.0123965 |