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15-Deoxy-Δ(12,14)-Prostaglandin J(2) Inhibits Osteolytic Breast Cancer Bone Metastasis and Estrogen Deficiency-Induced Bone Loss
Breast cancer is the major cause of cancer death in women worldwide. The most common site of metastasis is bone. Bone metastases obstruct the normal bone remodeling process and aberrantly enhance osteoclast-mediated bone resorption, which results in osteolytic lesions. 15-deoxy-Δ(12,14)-prostaglandi...
Autores principales: | Kim, Ki Rim, Kim, Hyun Jeong, Lee, Sun Kyoung, Ma, Gwang Taek, Park, Kwang Kyun, Chung, Won Yoon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393227/ https://www.ncbi.nlm.nih.gov/pubmed/25859665 http://dx.doi.org/10.1371/journal.pone.0122764 |
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