Thrombomodulin Contributes to Gamma Tocotrienol-Mediated Lethality Protection and Hematopoietic Cell Recovery in Irradiated Mice

Systemic administration of recombinant thrombomodulin (TM) confers radiation protection partly by accelerating hematopoietic recovery. The uniquely potent radioprotector gamma tocotrienol (GT3), in addition to being a strong antioxidant, inhibits the enzyme hydroxy-methyl-glutaryl-coenzyme A reducta...

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Detalles Bibliográficos
Autores principales: Pathak, Rupak, Shao, Lijian, Ghosh, Sanchita P., Zhou, Daohong, Boerma, Marjan, Weiler, Hartmut, Hauer-Jensen, Martin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393275/
https://www.ncbi.nlm.nih.gov/pubmed/25860286
http://dx.doi.org/10.1371/journal.pone.0122511

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393275/
https://www.ncbi.nlm.nih.gov/pubmed/25860286
http://dx.doi.org/10.1371/journal.pone.0122511

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