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aPKC Phosphorylation of HDAC6 Results in Increased Deacetylation Activity

The Class II histone deacetylase, HDAC6, has been shown to be involved in cell motility, aggresome formation and mitochondria transport. HDAC6 deacetylase activity regulates α-tubulin acetylation levels and thus plays a critical role in these processes. In turn, HDAC6 activity can be regulated by in...

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Detalles Bibliográficos
Autores principales: Du, Yifeng, Seibenhener, Michael L., Yan, Jin, Jiang, Jianxiong, Wooten, Michael C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393284/
https://www.ncbi.nlm.nih.gov/pubmed/25860570
http://dx.doi.org/10.1371/journal.pone.0123191