Expression and Function of S100A8/A9 (Calprotectin) in Human Typhoid Fever and the Murine Salmonella Model

BACKGROUND: Typhoid fever, caused by the Gram-negative bacterium Salmonella enterica serovar Typhi, is a major cause of community-acquired bacteremia and death worldwide. S100A8 (MRP8) and S100A9 (MRP14) form bioactive antimicrobial heterodimers (calprotectin) that can activate Toll-like receptor 4,...

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Detalles Bibliográficos
Autores principales: De Jong, Hanna K., Achouiti, Ahmed, Koh, Gavin C. K. W., Parry, Christopher M., Baker, Stephen, Faiz, Mohammed Abul, van Dissel, Jaap T., Vollaard, Albert M., van Leeuwen, Ester M. M., Roelofs, Joris J. T. H., de Vos, Alex F., Roth, Johannes, van der Poll, Tom, Vogl, Thomas, Wiersinga, Willem Joost
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393299/
https://www.ncbi.nlm.nih.gov/pubmed/25860480
http://dx.doi.org/10.1371/journal.pntd.0003663

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393299/
https://www.ncbi.nlm.nih.gov/pubmed/25860480
http://dx.doi.org/10.1371/journal.pntd.0003663

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