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Genome-wide blood DNA methylation alterations at regulatory elements and heterochromatic regions in monozygotic twins discordant for obesity and liver fat

BACKGROUND: The current epidemic of obesity and associated diseases calls for swift actions to better understand the mechanisms by which genetics and environmental factors affect metabolic health in humans. Monozygotic (MZ) twin pairs showing discordance for obesity suggest that epigenetic influence...

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Detalles Bibliográficos
Autores principales: Ollikainen, Miina, Ismail, Khadeeja, Gervin, Kristina, Kyllönen, Anjuska, Hakkarainen, Antti, Lundbom, Jesper, Järvinen, Elina A, Harris, Jennifer R, Lundbom, Nina, Rissanen, Aila, Lyle, Robert, Pietiläinen, Kirsi H, Kaprio, Jaakko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393626/
https://www.ncbi.nlm.nih.gov/pubmed/25866590
http://dx.doi.org/10.1186/s13148-015-0073-5