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TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma

BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by widespread epidemiological and molecular heterogeneity. Previous work showed that in the western part of North Africa, a region of low incidence of HCC, mutations are scarce for this tumor type. As epigenetic changes are considered possi...

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Detalles Bibliográficos
Autores principales: Rebbani, Khadija, Marchio, Agnès, Ezzikouri, Sayeh, Afifi, Rajaa, Kandil, Mostafa, Bahri, Olfa, Triki, Henda, Essaid El Feydi, Abdellah, Dejean, Anne, Benjelloun, Soumaya, Pineau, Pascal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393630/
https://www.ncbi.nlm.nih.gov/pubmed/25889455
http://dx.doi.org/10.1186/s12943-015-0340-2