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TP53 R72P polymorphism modulates DNA methylation in hepatocellular carcinoma
BACKGROUND: Hepatocellular carcinoma (HCC) is characterized by widespread epidemiological and molecular heterogeneity. Previous work showed that in the western part of North Africa, a region of low incidence of HCC, mutations are scarce for this tumor type. As epigenetic changes are considered possi...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393630/ https://www.ncbi.nlm.nih.gov/pubmed/25889455 http://dx.doi.org/10.1186/s12943-015-0340-2 |