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Rho-kinase mediates diphosphorylation of myosin regulatory light chain in cultured uterine, but not vascular smooth muscle cells

Phosphorylation of myosin regulatory light chain (RLC) triggers contraction in smooth muscle myocytes. Dephosphorylation of phosphorylated RLC (pRLC) is mediated by myosin RLC phosphatase (MLCP), which is negatively regulated by rho-associated kinase (ROK). We have compared basal and stimulated conc...

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Detalles Bibliográficos
Autores principales: Aguilar, Hector N, Tracey, Curtis N, Zielnik, Barbara, Mitchell, Bryan F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BlackWell Publishing Ltd 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393726/
https://www.ncbi.nlm.nih.gov/pubmed/22947248
http://dx.doi.org/10.1111/j.1582-4934.2012.01625.x