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Treatment of advanced gastrointestinal tumors with genetically modified autologous mesenchymal stromal cells (TREAT-ME1): study protocol of a phase I/II clinical trial

BACKGROUND: Adenocarcinoma originating from the digestive system is a major contributor to cancer-related deaths worldwide. Tumor recurrence, advanced local growth and metastasis are key factors that frequently prevent these tumors from curative surgical treatment. Preclinical research has demonstra...

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Detalles Bibliográficos
Autores principales: Niess, Hanno, von Einem, Jobst C, Thomas, Michael N, Michl, Marlies, Angele, Martin K, Huss, Ralf, Günther, Christine, Nelson, Peter J, Bruns, Christiane J, Heinemann, Volker
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393860/
https://www.ncbi.nlm.nih.gov/pubmed/25879229
http://dx.doi.org/10.1186/s12885-015-1241-x