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A pilot feasibility, safety and biological efficacy multicentre trial of therapeutic hypercapnia after cardiac arrest: study protocol for a randomized controlled trial

BACKGROUND: Cardiac arrest causes ischaemic brain injury. Arterial carbon dioxide tension (PaCO(2)) is a major determinant of cerebral blood flow. Thus, mild hypercapnia in the 24 h following cardiac arrest may increase cerebral blood flow and attenuate such injury. We describe the Carbon Control an...

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Detalles Bibliográficos
Autores principales: Eastwood, Glenn M, Schneider, Antoine G, Suzuki, Satoshi, Bailey, Michael, Bellomo, Rinaldo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393877/
https://www.ncbi.nlm.nih.gov/pubmed/25872502
http://dx.doi.org/10.1186/s13063-015-0676-3