Type I Saikosaponins A and D Inhibit Osteoclastogenesis in Bone Marrow-Derived Macrophages and Osteolytic Activity of Metastatic Breast Cancer Cells

Many osteopenic disorders, including a postmenopausal osteoporosis and lytic bone metastasis in breast and prostate cancers, are linked with a hyperosteoclast activity due to increased receptor activator of nuclear factor kappa-B ligand (RANKL) expression in osteoblastic/stromal cells. Therefore, in...

Descripción completa

Detalles Bibliográficos
Autores principales: Shin, Ji-Eun, Kim, Hyun-Jeong, Kim, Ki-Rim, Lee, Sun Kyoung, Park, Junhee, Kim, Hyungkeun, Park, Kwang-Kyun, Chung, Won-Yoon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393913/
https://www.ncbi.nlm.nih.gov/pubmed/25892999
http://dx.doi.org/10.1155/2015/582437

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393913/
https://www.ncbi.nlm.nih.gov/pubmed/25892999
http://dx.doi.org/10.1155/2015/582437

Ejemplares similares