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Analysis of the Expression and Polymorphism of APOE, HSP, BDNF, and GRIN2B Genes Associated with the Neurodegeneration Process in the Pathogenesis of Primary Open Angle Glaucoma

Glaucoma is characterized by optic neuropathy of the RGC or retinal nerve fiber. The aim of this study was to evaluate a relationship between the neurodegenerative genes' polymorphisms of the APOE (rs449647), BDNF (rs2030324), GRIN2B (rs3764028), and HSP70-1 (rs1043618) and the occurrence risk...

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Detalles Bibliográficos
Autores principales: Nowak, Alicja, Majsterek, Ireneusz, Przybyłowska-Sygut, Karolina, Pytel, Dariusz, Szymanek, Katarzyna, Szaflik, Jerzy, Szaflik, Jacek P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393917/
https://www.ncbi.nlm.nih.gov/pubmed/25893192
http://dx.doi.org/10.1155/2015/258281