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RC-3095, a Selective Gastrin-Releasing Peptide Receptor Antagonist, Does Not Protect the Lungs in an Experimental Model of Lung Ischemia-Reperfusion Injury

RC-3095, a selective GRPR antagonist, has been shown to have anti-inflammatory properties in different models of inflammation. However, its protective effect on lungs submitted to lung ischemia-reperfusion injury has not been addressed before. Then, we administrated RC-3095 intravenously before and...

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Detalles Bibliográficos
Autores principales: Oliveira-Freitas, Vera L., Thomaz, Leonardo Dalla Giacomassa Rocha, Simoneti, Lucas Elias Lise, Malfitano, Christiane, De Angelis, Kátia, Ulbrich, Jane Maria, Schwartsmann, Gilberto, Andrade, Cristiano Feijó
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4393930/
https://www.ncbi.nlm.nih.gov/pubmed/25893195
http://dx.doi.org/10.1155/2015/496378