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p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies

Ca(2+) transfer from the endoplasmic reticulum (ER) to the mitochondria critically controls cell survival and cell death decisions. Different oncogenes and deregulation of tumor suppressors exploit this mechanism to favor the survival of altered, malignant cells. Two recent studies of the Pinton tea...

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Detalles Bibliográficos
Autores principales: Bittremieux, Mart, Bultynck, Geert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394128/
https://www.ncbi.nlm.nih.gov/pubmed/25897426