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p53 and Ca(2+) signaling from the endoplasmic reticulum: partners in anti-cancer therapies
Ca(2+) transfer from the endoplasmic reticulum (ER) to the mitochondria critically controls cell survival and cell death decisions. Different oncogenes and deregulation of tumor suppressors exploit this mechanism to favor the survival of altered, malignant cells. Two recent studies of the Pinton tea...
Autores principales: | Bittremieux, Mart, Bultynck, Geert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394128/ https://www.ncbi.nlm.nih.gov/pubmed/25897426 |
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