Characterization of a murine model of metastatic human non-small cell lung cancer and effect of CXCR4 inhibition on the growth of metastases

Despite successful preclinical testing carried out through the use of subcutaneous xenografted tumors, many anti-cancer agents have gone on to fail in human trials. One potential factor accounting for this discrepancy may relate to the inadequacy of the commonly employed preclinical models to recapi...

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Detalles Bibliográficos
Autores principales: Singla, Arvind K., Downey, Charlene M., Bebb, Gwyn D., Jirik, Frank R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394132/
https://www.ncbi.nlm.nih.gov/pubmed/25897429

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394132/
https://www.ncbi.nlm.nih.gov/pubmed/25897429

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