Screening of deoxyribozyme with high reversal efficiency against multidrug resistance in breast carcinoma cells

Specific inhibition of P-glycoprotein (Pgp) expression, which is encoded by multidrug resistance gene-1 (MDR1), is considered a well-respected strategy to overcome multidrug resistance (MDR). Deoxyribozymes (DRz) are catalytic nucleic acids that could cleave a target RNA in sequence-specific manner....

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Detalles Bibliográficos
Autores principales: Gao, Peng, Wei, Jun-Min, Li, Peng-Yu, Zhang, Cui-Juan, Jian, Wen-Cheng, Zhang, Yu-Hua, Xing, Ai-Yan, Zhou, Geng-Yin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2011
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394223/
https://www.ncbi.nlm.nih.gov/pubmed/21155975
http://dx.doi.org/10.1111/j.1582-4934.2010.01240.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394223/
https://www.ncbi.nlm.nih.gov/pubmed/21155975
http://dx.doi.org/10.1111/j.1582-4934.2010.01240.x

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