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Down-regulated miR-331–5p and miR-27a are associated with chemotherapy resistance and relapse in leukaemia
Multidrug resistance (MDR) and disease relapse are challenging clinical problems in the treatment of leukaemia. Relapsed disease is frequently refractory to chemotherapy and exhibits multiple drug resistance. Therefore, it is important to identify the mechanism by which cancer cells develop resistan...
Autores principales: | , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
2011
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394226/ https://www.ncbi.nlm.nih.gov/pubmed/21070600 http://dx.doi.org/10.1111/j.1582-4934.2010.01213.x |