RhoA and ROCK mediate histamine-induced vascular leakage and anaphylactic shock

Histamine-induced vascular leakage is an integral component of many highly prevalent human diseases, including allergies, asthma, and anaphylaxis. Yet, how histamine induces the disruption of the endothelial barrier is not well defined. By using genetically modified animal models, pharmacologic inhi...

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Detalles Bibliográficos
Autores principales: Mikelis, Constantinos M., Simaan, May, Ando, Koji, Fukuhara, Shigetomo, Sakurai, Atsuko, Amornphimoltham, Panomwat, Masedunskas, Andrius, Weigert, Roberto, Chavakis, Triantafyllos, Adams, Ralf, Offermanns, Stefan, Mochizuki, Naoki, Zheng, Yi, Gutkind, J. Silvio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394241/
https://www.ncbi.nlm.nih.gov/pubmed/25857352
http://dx.doi.org/10.1038/ncomms7725

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394241/
https://www.ncbi.nlm.nih.gov/pubmed/25857352
http://dx.doi.org/10.1038/ncomms7725

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