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Tumor Progression Locus 2 (Tpl2) Kinase as a Novel Therapeutic Target for Cancer: Double-Sided Effects of Tpl2 on Cancer

Tumor progression locus 2 (Tpl2) is a mitogen-activated protein kinase (MAPK) kinase kinase (MAP3K) that conveys various intra- and extra-cellular stimuli to effector proteins of cells provoking adequate adoptive responses. Recent studies have elucidated that Tpl2 is an indispensable signal transduc...

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Detalles Bibliográficos
Autores principales: Lee, Hye Won, Choi, Han Yong, Joo, Kyeung Min, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394431/
https://www.ncbi.nlm.nih.gov/pubmed/25723737
http://dx.doi.org/10.3390/ijms16034471