Ceramide-Induced Apoptosis in Renal Tubular Cells: A Role of Mitochondria and Sphingosine-1-Phoshate

Ceramide is synthesized upon stimuli, and induces apoptosis in renal tubular cells (RTCs). Sphingosine-1 phosphate (S1P) functions as a survival factor. Thus, the balance of ceramide/S1P determines ceramide-induced apoptosis. Mitochondria play a key role for ceramide-induced apoptosis by altered mit...

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Detalles Bibliográficos
Autor principal: Ueda, Norishi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394466/
https://www.ncbi.nlm.nih.gov/pubmed/25751724
http://dx.doi.org/10.3390/ijms16035076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394466/
https://www.ncbi.nlm.nih.gov/pubmed/25751724
http://dx.doi.org/10.3390/ijms16035076

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