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The Infection Efficiency and Replication Ability of Circularized HBV DNA Optimized the Linear HBV DNA in Vitro and in Vivo

Studies on molecular mechanisms of the persist infection of hepatitis B virus have been hampered by a lack of a robust animal model. We successfully established a simple, versatile, and reproducible HBV persist infection model in vitro and in vivo with the circularized HBV DNA. The cells and mice we...

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Detalles Bibliográficos
Autores principales: Li, Xiaosong, Zhu, Junke, Lai, Guoqi, Yan, Lei, Hu, Jieli, Chen, Juan, Tang, Ni, Huang, Ailong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394468/
https://www.ncbi.nlm.nih.gov/pubmed/25751726
http://dx.doi.org/10.3390/ijms16035141