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The Infection Efficiency and Replication Ability of Circularized HBV DNA Optimized the Linear HBV DNA in Vitro and in Vivo
Studies on molecular mechanisms of the persist infection of hepatitis B virus have been hampered by a lack of a robust animal model. We successfully established a simple, versatile, and reproducible HBV persist infection model in vitro and in vivo with the circularized HBV DNA. The cells and mice we...
Autores principales: | Li, Xiaosong, Zhu, Junke, Lai, Guoqi, Yan, Lei, Hu, Jieli, Chen, Juan, Tang, Ni, Huang, Ailong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394468/ https://www.ncbi.nlm.nih.gov/pubmed/25751726 http://dx.doi.org/10.3390/ijms16035141 |
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