Novel Cholesterol-Based Cationic Lipids as Transfecting Agents of DNA for Efficient Gene Delivery

The design, synthesis and biological evaluation of the cationic lipid gene delivery vectors based on cholesterol and natural amino acids lysine or histidine are described. Cationic liposomes composed of the newly synthesized cationic lipids 1a or 1b and neutral lipid DOPE (1,2-dioleoyl-l-α-glycero-3...

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Detalles Bibliográficos
Autores principales: Ju, Jia, Huan, Meng-Lei, Wan, Ning, Qiu, Hai, Zhou, Si-Yuan, Zhang, Bang-Le
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394498/
https://www.ncbi.nlm.nih.gov/pubmed/25768346
http://dx.doi.org/10.3390/ijms16035666

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394498/
https://www.ncbi.nlm.nih.gov/pubmed/25768346
http://dx.doi.org/10.3390/ijms16035666

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