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A Pharmacogenetics Study in Mozambican Patients Treated with Nevirapine: Full Resequencing of TRAF3IP2 Gene Shows a Novel Association with SJS/TEN Susceptibility

Steven–Johnson Syndrome (SJS) and Toxic Epidermal Necrolysis (TEN) are severe adverse drug reactions, characterized by extensive epidermal detachment and erosions of mucous membrane. SJS/TEN is one of the most serious adverse reactions to Nevirapine (NVP) treatment, commonly used in developing count...

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Detalles Bibliográficos
Autores principales: Ciccacci, Cinzia, Rufini, Sara, Mancinelli, Sandro, Buonomo, Ersilia, Giardina, Emiliano, Scarcella, Paola, Marazzi, Maria C., Novelli, Giuseppe, Palombi, Leonardo, Borgiani, Paola
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394508/
https://www.ncbi.nlm.nih.gov/pubmed/25775161
http://dx.doi.org/10.3390/ijms16035830