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Candesartan restores pressure-induced vasodilation and prevents skin pressure ulcer formation in diabetic mice

BACKGROUND: Angiotensin II type 1 receptor (AT1R) blockers have beneficial effects on neurovascular complications in diabetes and in organ’s protection against ischemic episodes. The present study examines whether the AT1R blocker candesartan (1) has a beneficial effect on diabetes-induced alteratio...

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Detalles Bibliográficos
Autores principales: Danigo, Aurore, Nasser, Mohamad, Bessaguet, Flavien, Javellaud, James, Oudart, Nicole, Achard, Jean-Michel, Demiot, Claire
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4394592/
https://www.ncbi.nlm.nih.gov/pubmed/25888905
http://dx.doi.org/10.1186/s12933-015-0185-4